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GlossaryPhosphoinositide 3-kinase

enzyme involved in cell growth and survival signaling

Phosphoinositide 3-kinase (PI3K) is an enzyme that plays a crucial role in cell growth, proliferation, and survival by activating signaling pathways inside cells. It is particularly important in the context of cancer research, as abnormal PI3K activity can lead to uncontrolled cell division and tumor growth.

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research Role of Phosphatidylinositol 3-Kinase Signaling Pathway in Radiation-Induced Liver Injury

6 citations , July 2020 in “The Kaohsiung Journal of Medical Sciences”

Inhibiting the PI3K/Akt pathway may help prevent radiation-induced liver injury.

research Induction of Versican by Ascorbic Acid 2-Phosphate in Dermal Papilla Cells

22 citations , April 2006 in “Journal of Dermatological Science”

Vitamin C derivative increases versican in cells, potentially aiding hair growth.

research L-Ascorbic Acid 2-Phosphate Promotes Elongation of Hair Shafts via the Secretion of Insulin-Like Growth Factor-1 from Dermal Papilla Cells Through Phosphatidylinositol 3-Kinase

34 citations , March 2009 in “British journal of dermatology/British journal of dermatology, Supplement”

Vitamin C derivative helps hair grow longer by making cells produce a growth factor through a specific cellular pathway.

research Phosphatidylinositol 3-Kinase/Akt-Dependent and Independent Protection Against Apoptosis in Normal Human Melanocytes

16 citations , October 2004 in “Journal of Investigative Dermatology”

Normal human melanocytes can avoid cell death through multiple pathways.

research Identification and Characterization of the Hamster Polyomavirus Middle T Antigen

52 citations , June 1991 in “Journal of Virology”

The hamster polyomavirus middle T antigen is linked to tumors in hamsters and associates with a specific tyrosine kinase.

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