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research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing

188 citations, October 2012 in “The AAPS Journal”

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

research Optimization of Bear Oil Extraction Process and Hair Growth Activity

March 2024 in “Molecules/Molecules online/Molecules annual”

Enzymatically extracted bear oil has more unsaturated fats and significantly increases hair growth in mice.

Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride

research Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride

6 citations, March 2021 in “International Journal of Pharmaceutics”

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling

18 citations, June 1999 in “Statistical Methods in Medical Research”

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

research Assessment of the Pharmacokinetic-Pharmacodynamic Interaction Between Terazosin and Finasteride

6 citations, December 1996 in “The Journal of Clinical Pharmacology”

Terazosin and finasteride together cause no major issues.

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community The story of RU58841/ PSK3841

in Research 622 upvotes 4 months ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

community Anyone actually stuck with Dutasteride after switching from Finasteride?

in Finasteride/Dutasteride 61 upvotes 1 year ago

The conversation discusses switching from finasteride to dutasteride for hair loss treatment, with mixed experiences regarding shedding and effectiveness. Some users also mention using minoxidil and RU58841 alongside these treatments.

community CB-03-01: I need help

in Treatment 7 upvotes 3 years ago

The user stopped using finasteride and RU58841 and is considering CB-03-01 for androgenic alopecia but is concerned about the cost and effectiveness, especially at a lower dose than in clinical trials. They are also using minoxidil, micro-needling, and nizoral shampoo but are unsure about the correct application method for CB-03-01.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 4 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 82 upvotes 5 months ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

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