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In this study, researchers developed a pH-sensitive dendritic polyglycerol nanogel to measure pH inside hair follicles using an ex vivo porcine ear model, finding that the pH increases from 6.5 at the skin surface to 7.4 in deeper follicle areas, without observed toxicity.

This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.

This study used melamine formaldehyde particles to measure a pH gradient along the hair shaft, showing a significant pH decrease from the hair sheath to the external shaft.

This study explains the formulation and evaluation of a natural polyherbal shampoo, which effectively colors hair and provides conditioning without the dermal and systemic toxicity risks of synthetic dyes, offering an effective alternative to conventional products.

This study found that genipin-based pigments, accelerated by riboflavin and blue-light photocatalysis, achieved commercial-level hair dye results with enhanced gloss and excellent color retention while reducing cuticle disruption, offering a potentially safer and faster alternative to traditional hair coloration methods.