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research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

23 citations , October 2008 in “Journal of medicinal chemistry”

This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.

research Electric Stimulation at 448 kHz Modulates Proliferation and Differentiation of Follicle Dermal Papilla Cells

October 2024 in “Cosmetics”

In this study, subthermal RF-CRET currents were found to alter key molecular mechanisms in dermal papilla cells, promoting proliferation and survival while enhancing markers associated with hair growth and maintenance, suggesting potential benefits for hair regeneration.

research Long-term stability of frozen platelet-rich plasma under −80 °C storage condition

5 citations , June 2024 in “Regenerative Therapy”

This study found that freezing PRP at -80 °C for up to a year maintains most growth factor levels, with EGF and IGF even higher than in fresh samples.

research Platelet factor 4 inhibits human hair follicle growth and promotes androgen receptor expression in human dermal papilla cells

4 citations , September 2020 in “PeerJ”

This study found that platelet factor 4 in platelet-rich plasma suppresses human hair follicle growth and alters related gene expressions, suggesting potential implications for its use in hair loss treatment.

New Hair Care Ingredients Introduced in March 2011

research New hair care ingredients

March 2011 in “Focus on surfactants”

Several companies launched new hair care ingredients in 2011 to improve conditioning, color retention, combability, and heat protection.

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Clinics

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Community Join

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community My DHT levels on 1400mg testosterone per week and 0.5mg dutasteride daily

346 upvotes 2 months ago

A bodybuilder uses 1400mg testosterone weekly, 400mg equipoise, and GH, with 0.5mg dutasteride daily to stabilize hair loss and manage DHT levels. The user reports no side effects from dutasteride and finds it effective, while also discussing costs and effectiveness of other treatments like RU58841 and minoxidil.

community 100 days on fin+min+dermastamp

in Progress Pictures 49 upvotes 5 months ago

A user shared progress pictures after 100 days of using finasteride, topical minoxidil, and dermastamping, with oral minoxidil added two weeks ago, reporting no side effects. Some users praised the results, while others questioned the effectiveness of dermastamping and the visibility of hair growth.

community 5 months in using rogaine foam 5%.

in Progress Pictures 15 upvotes 5 months ago

The user has been using 5% minoxidil foam for 5 months with noticeable results and is considering adding finasteride. Suggestions include adding finasteride, using hair fiber spray, and trying microneedling for better results.

community Is this VIOFAIRY Minoxidil brand good

in Minoxidil 2 upvotes 2 years ago

A user has been using a new brand of minoxidil called VIOFAIRY for six months and finds it effective, though the labeling has misspellings. They are seeking feedback from others who have tried this brand.

community 6 month evolution. Dutas 0.5 + 3 mg oral Minox + Vitamin D3, Zinc, Biotin daily (Reposted W/pics)

32 upvotes 10 months ago

The user shared their successful hair regrowth experience using Dutas, oral and topical minoxidil, vitamin D3, zinc, biotin, a laser cap, natural shampoos, ketoconazole shampoo, retinoic acid lotion, and mesotherapy. They reported no side effects and significant improvement in hair thickness and color over six months.

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Experts

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