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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
      • Is cyproterone only for women, or can men use it too? Cyproterone acetate is not a women-only drug — published reports describe use in men for prostate cancer, paraphilic disorders and gender-affirming therapy — but it is not FDA-approved for any indication, and European regulators restricted higher doses over a dose-related meningioma risk.

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Fluridil

      a topical anti-androgen with less systemic involvement