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    GlossaryPER1 (Period Circadian Regulator 1)

    gene regulating body's internal clock and biological rhythms

    PER1, or Period Circadian Regulator 1, is a gene that plays a crucial role in regulating the body's internal clock, or circadian rhythm. This gene helps control various biological processes, including sleep-wake cycles, hormone release, and other daily physiological patterns. In the context of hair biology, disruptions in circadian rhythms can potentially affect hair growth cycles and contribute to conditions like alopecia.

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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Adenosine

      nucleoside used for hair regrowth stimulant properties

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      community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

      in Progress Pictures  492 upvotes 2 years ago
      A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

      community How to reduce cortisol (stress hormone) naturally?

      in Chat  36 upvotes 2 years ago
      The conversation discusses natural ways to reduce cortisol, such as avoiding caffeine, getting proper sleep, syncing with the sun, walking in nature, breathing exercises, increasing calories, and not doing keto. Magnesium supplements are recommended for stress reduction.

      community 6 months into Dutasteride and my hair is way worse than before

      in Finasteride/Dutasteride  76 upvotes 7 months ago
      After six months on Dutasteride, the user's hair is worse than before, despite previously trying finasteride and RU/Fluridil without success. Some suggest continuing Dutasteride and adding progress photos, while others share their positive experiences or advise sticking to one treatment for at least a year.

      community 3 months. Dut, Min, Keto, Vitamin D, exercise

      in Progress Pictures  353 upvotes 2 years ago
      A user's experience using dutasteride, minoxidil, ketoconazole, vitamin D, scalp massage, exercise, and avoiding vaping and 2-in-1 shampoo/conditioner to treat hair loss; they also discussed the side effects of finasteride.