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research Frontal Fibrosing Alopecia: A Case Report of a 66-Year-Old Caucasian Woman

July 2015 in “Journal of the Dermatology Nurses’ Association”

A 66-year-old woman experienced hair loss due to Frontal Fibrosing Alopecia, a condition with no consistently effective treatment, but it usually stabilizes over time. More research is needed for better understanding and treatment options.

research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata

134 citations , July 2020 in “Experimental dermatology”

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

research Neuroimmunoendocrine Circuitry of the Brain-Skin Connection

293 citations , November 2005 in “Trends in Immunology”

Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.

research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions

61 citations , September 2010 in “Journal of Dermatological Science”

Stress hormones and autoimmune reactions can cause hair loss.

Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

22 citations , August 2009 in “Evidence-based Complementary and Alternative Medicine”

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Why is my dermatologist strictly against derma stamping/derma rolling?

in Microneedling 27 upvotes 4 months ago

Dermatologists often advise against at-home microneedling due to risks of scarring, infection, and improper technique. Professional guidance is recommended for safe and effective use, with some users reporting positive results when done correctly.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 415 upvotes 5 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community A hill on which I will die: The DHT itch absolutely exists

in Research/Science 210 upvotes 1 year ago

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 20 upvotes 3 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

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