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research Frontal Fibrosing Alopecia: A Case Report of a 66-Year-Old Caucasian Woman

July 2015 in “Journal of the Dermatology Nurses’ Association”

A 66-year-old woman experienced hair loss due to Frontal Fibrosing Alopecia, a condition with no consistently effective treatment, but it usually stabilizes over time. More research is needed for better understanding and treatment options.

research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions

61 citations , September 2010 in “Journal of Dermatological Science”

Stress hormones and autoimmune reactions can cause hair loss.

research Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells

175 citations , December 2014 in “PLoS Biology”

Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.

research Acne and Acneiform Eruptions

2 citations , January 2011 in “Elsevier eBooks”

Early treatment of acne is crucial to prevent scarring and psychological effects.

Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

22 citations , August 2009 in “Evidence-based Complementary and Alternative Medicine”

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

in Research/Science 28 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 1 month ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community A hill on which I will die: The DHT itch absolutely exists

in Research/Science 210 upvotes 1 year ago

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 18 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

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