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In this study, bright light exposure during the daytime did not significantly affect clock gene expression in humans, although Rev-erb-ß expression appeared stronger under bright light compared to dim light.

This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.

This study found that activation of delta-opioid receptors in keratinocytes may delay the expression of the PER2 gene, suggesting a possible link to cancer development through circadian rhythm disruption.

This study found that leukocytes and beard hair follicle cells have an endogenous circadian clock, with PER1 and PER3 expression possibly serving as biomarkers for assessing individual biological clock traits.

This study found that the circadian clock regulates the activation and heterogeneity of hair follicle bulge stem cells, affecting tissue homeostasis and tumorigenesis risk in mouse skin.