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research Uptake and Utilisation of Amino Acids by Human Hair Follicles and Related Cells

1 citations , January 1996

This study found that cysteine and arginine are crucial for hair growth in hair follicles, with cysteine affecting hair fibre diameter and arginine involved in protein incorporation and energy metabolism.

research Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8

61 citations , May 2016 in “Scientific reports”

This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.

research Author response: Structural basis of malodour precursor transport in the human axilla

1 citations , June 2018

This study uncovered how Staphylococcus hominis transports an odor precursor molecule, potentially leading to new ways to control body odor production in humans.

research Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi

41 citations , March 2017 in “PLoS neglected tropical diseases”

This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.

research Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle

13 citations , January 2021 in “Histochemistry and Cell Biology”

In this study, human hair follicles showed varying expression of cholesterol transport proteins during the hair cycle, suggesting a potential role of cholesterol in hair growth and cycling.

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community Potential ( but not yet confirmed ) pp405 leak through korean media.

233 upvotes 11 months ago

A peptide-based hair loss treatment, PP405, reportedly increased hair density by 62% in 90 days, but these claims are unverified and met with skepticism. Users compared PP405 to Minoxidil and Finasteride, expressing doubts about its effectiveness without more evidence.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Story time! The Great Unbalding (PP405)

230 upvotes 11 months ago

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM

4 upvotes 2 years ago

The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.

community peptides seems to have dramatically decreased hairloss!

85 upvotes 4 months ago

Peptides like GHK-Cu, BPC-157, and TB-500 have significantly reduced hair loss, with GHK-Cu being particularly effective. The discussion also covers the high cost of these peptides and explores more affordable purchasing options.

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learn PP405

Did you know PP405 peptides can help protect your follicles from DHT? PP405 is not a peptide and does not block DHT: it is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier, aimed at waking dormant follicles. Its registered Phase 2 trial (NCT06393452) measured safety and tolerability in 78 adults with pattern hair loss; it is not approved and not for sale.

learn Marine Collagen Peptides (Nutrafol)

learn retinol

Can retinol help enhance the absorption of ingredients like minoxidil or peptides? Retinol may enhance absorption of minoxidil and peptides by modifying skin barrier properties.

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

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