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Evaluation of Efficacy of Water-Soluble Fraction of Rhus Semialata Gall Extract and Penta-O-Galloyl-β-D-Glucose on Mitigation of Hair Loss: An In Vitro and Randomized Double-Blind Placebo-Controlled Clinical Study

research Evaluation of Efficacy of Water-Soluble Fraction of Rhus Semialata Gall Extract and Penta-O-Galloyl-β-D-Glucose on Mitigation of Hair Loss: An In Vitro and Randomized Double-Blind Placebo-Controlled Clinical Study

April 2025 in “Antioxidants”

Rhus semialata gall extract and Penta-O-Galloyl-β-D-Glucose may effectively reduce hair loss.

Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex

research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex

37 citations, January 2015 in “Evidence-based Complementary and Alternative Medicine”

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

research Trapa Bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice

July 2023 in “International Journal of Molecular Sciences”

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Alleviation of Androgenetic Alopecia with Aqueous Paeonia Lactiflora and Poria Cocos Extract Intake Through Suppressing the Steroid Hormone and Inflammatory Pathway

research Alleviation of Androgenetic Alopecia with Aqueous Paeonia Lactiflora and Poria Cocos Extract Intake Through Suppressing the Steroid Hormone and Inflammatory Pathway

4 citations, November 2021 in “Pharmaceuticals”

Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.

research Caffeic Acid N-[3,5-Bis(Trifluoromethyl)Phenyl] Amide as a Non-Steroidal Inhibitor for Steroid 5α-Reductase Type 1 Using a Human Keratinocyte Cell-Based Assay and Molecular Dynamics

December 2022 in “Scientific Reports”

Compound 4 is a promising treatment for hair loss with low toxicity.

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Community Join

5 / 8 results

community 4 years on fin and totally stopped hair loss

in Progress Pictures 92 upvotes 1 year ago

A user stopped hair loss after taking finasteride daily for four years, with minimal regrowth and no side effects. They believe stress initially caused their hair loss.

community 1 year topical fin/min coupled with frontal HT

in Progress Pictures 192 upvotes 1 year ago

The user experienced significant hair improvement after one year using topical finasteride and minoxidil, combined with a hair transplant at the front. They switched from oral to topical finasteride due to side effects and are satisfied with the results, especially at the temples.

community Update : 7 months on DUT every other day

in Is this regrowth? 100 upvotes 3 weeks ago

The user experienced significant hair improvement after 7 months of using Dutasteride (DUT) every other day, with no side effects, unlike previous experiences with Finasteride (FIN) and Minoxidil (MIN). The user plans to continue DUT for up to 24 months and is considering a hair transplant for further results.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 50 upvotes 8 months ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community Can Fin + Min save my hair? [20M]

in Satire 3168 upvotes 1 year ago

A user is considering using finasteride and minoxidil to address hair loss, particularly at the temples and crown. Responses include encouragement, humor, and additional suggestions like using a derma roller.

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