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Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats

research Long-Term Oral Administration of 5α-Reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats

34 citations, September 2013 in “Urology”

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases

2 citations, May 2022 in “International Journal of Impotence Research”

Finasteride may be linked to Peyronie’s disease, but more research is needed.

research Exploring the Efficacy of Testosterone Undecanoate in Male Children with 5α-Reductase Deficiency

5 citations, December 2021 in “Pediatric investigation”

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia

research An Observational Retrospective Evaluation of 79 Young Men with Long-Term Adverse Effects After Use of Finasteride Against Androgenetic Alopecia

43 citations, January 2016 in “International Journal of Andrology”

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

research Hair Coil Penile Tourniquet Syndrome in an Unusual Age

4 citations, January 2015 in “Case reports in urology”

An 8-year-old boy recovered from a rare case of penile tourniquet syndrome after hair removal surgery.

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Community Join

5 / 76 results

community NW5 at 19. How many grafts do I need?

ConstructionSome7534 in Transplants 142 upvotes 1 year ago

A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

community If you are under the age of 25 – MUST READ

B1GR0BB1E in Treatment 86 upvotes 2 years ago

23-year-old man tries finasteride, minoxidil, PRP, and dutasteride for hair loss. Recommends personalized routine and focusing on other life aspects.

community Update: 4 Month progress on Fin/Min plus dermaroller

TheOnlyPJizzle in Progress Pictures 559 upvotes 1 year ago

A user shared a 4-month update on their hair regrowth progress using finasteride, minoxidil, a dermaroller, ketoconazole shampoo, multivitamins, and biotin, and received positive reactions and inquiries from others. They also mentioned lifestyle changes such as quitting creatine, alcohol, and smoking, which may have contributed to their success.

community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

Slight_Gap_7067 in Progress Pictures 118 upvotes 5 months ago

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

community Used finasteride 10 years ago and I still suffer from severe ED. I have blood test results attached

fappoo11 in Finasteride 10 upvotes 6 years ago

A user took finasteride for hair loss 10 years ago, stopped after a month, and has since suffered from severe erectile dysfunction (ED) and other symptoms. They shared blood test results seeking advice for their condition, and others discussed similar experiences with finasteride and related drugs.

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