11 citations
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January 2018 in “Asian Journal of Andrology” Researchers observed that dutasteride and finasteride caused structural changes in the penises of both control and hypertensive rats, with dutasteride having a more pronounced effect on the corpus cavernosum.
34 citations
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September 2013 in “Urology” Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
December 2016 in “The Journal of Sexual Medicine” This study found that young men using finasteride for androgenic alopecia experienced erectile dysfunction and signs of erectile tissue fibrosis, alongside symptoms like low libido and mood changes.
February 2017 in “The Journal of Sexual Medicine” This study found that young men using finasteride for androgenic alopecia exhibited erectile tissue fibrosis and associated sexual dysfunction, including low libido and mood changes.
This article reviews the role of hormones in human penis development and associated conditions due to hormonal imbalances, but reports no new findings, suggesting hormone replacement can manage some conditions.