December 2025 in “Skin Appendage Disorders” This case report, one of the youngest on record, suggests that systemic stress might trigger pediatric sudden hair graying linked with diffuse alopecia areata, emphasizing the need to differentiate it from congenital silvery hair syndromes due to their distinct prognosis and treatment options.
January 2025 in “Figshare” In this case study, a 17-month-old girl experienced sudden hair depigmentation during septic shock hospitalization, suggesting systemic stress as a potential trigger for pediatric canities subita associated with diffuse alopecia areata.
January 2025 in “Figshare” This case report describes a 17-month-old girl who experienced sudden hair whitening during septic shock, suggesting systemic stress may trigger canities subita in young children and highlighting the need to distinguish it from congenital pigment dilution syndromes.
April 2020 in “IP Indian journal of clinical and experimental dermatology” This study explores autoimmune associations in pediatric patients with alopecia areata at a tertiary care center but reports no new clinical findings.
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January 2017 in “Journal of Pigmentary Disorders” This study explores the complex and not yet fully understood causes of premature hair greying, noting genetic factors such as Pax3 and MITE genes, potential defects in melanin transfer, and associations with certain syndromes, while stating that effective treatments are currently lacking.
