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research Pediatric androgenetic alopecia: A review

8 citations , August 2019 in “Journal of The American Academy of Dermatology”

This study found that androgenetic alopecia is a significant yet under-recognized cause of hair loss in children and adolescents, often linked to family history and typically diagnosed by clinical examination.

research Pediatric androgenetic alopecia: a retrospective review of clinical characteristics, hormonal assays and metabolic syndrome risk factors in 23 patients

3 citations , January 2022 in “Anais Brasileiros De Dermatologia”

This study suggests that pediatric androgenetic alopecia is often associated with metabolic syndrome risk factors, highlighting the importance of early diagnosis for potential future health complications.

research An International Multicenter, Retrospective Cohort Study of 203 Patients with Pediatric Androgenetic Alopecia

February 2025 in “Journal of the American Academy of Dermatology”

Standardized treatment protocols are needed for children with androgenetic alopecia.

research Pediatric androgenetic alopecia: an updated review

January 2023 in “Journal der Deutschen Dermatologischen Gesellschaft”

This review discusses pediatric androgenetic alopecia, emphasizing the diagnostic process and outlining potential treatments, but reports no new clinical results.

Androgenetic Alopecia in the Pediatric Population: A Retrospective Review of 57 Patients

research Androgenetic alopecia in the paediatric population: a retrospective review of 57 patients

53 citations , March 2010 in “British Journal of Dermatology”

This study found that androgenetic alopecia is the leading cause of hair loss in adolescents and may indicate endocrine disorders, emphasizing the need for accurate diagnosis.

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community Being Safe on Oral Minoxidil: tl;dr on the literature.

51 upvotes 1 year ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community just got diagnosed with androgenic alopecia at 15 and i feel like im at the end of my rope

46 upvotes 6 days ago

A 15-year-old is upset about androgenic alopecia and its effect on self-esteem. Recommendations include minoxidil, microneedling, hair systems, and focusing on self-confidence and therapy.

community The mechanism of androgenic alopecia

36 upvotes 11 months ago

DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Finasteride for alopecia: the definitive guide to using it correctly. Finasteride 1 mg daily blocks DHT and, in trials, slowed hair loss in most men over 6 to 12 months, though some men do not respond and the benefit lasts only while the drug is taken. It is prescription-only and carries a pregnancy contraindication.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Alfatradiol

Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn GT20029

Is GT20029 safe and effective for both men and women with androgenic alopecia? Not yet. GT20029 is an experimental drug: early trials suggest it is well tolerated, but its effectiveness and long-term safety are unproven, especially in women.

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Nanoxidil

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