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research Formulation and Characterization of Transethosomes for Enhanced Transdermal Delivery of Propranolol Hydrochloride

11 citations , January 2020 in “Micro and Nanosystems”

This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.

The Effect of Melatonin Implants Administered from December Until April on Plasma Prolactin, Triiodothyronine, and Thyroxine Concentrations and on the Timing of the Spring Moult in Cashmere Goats

research The effect of melatonin implants administered from December until April, on plasma prolactin, triiodothyronine and thyroxine concentrations and on the timing of the spring moult in cashmere goats

10 citations , April 1995 in “Animal Science/Animal science”

This study found that melatonin implants advanced the timing of the spring moult and increased hair follicle activity in adult cashmere goats, but had no significant effects on juvenile goats.

The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men

research The effect of St. John’s wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men

33 citations , November 2008 in “European Journal of Pharmaceutical Sciences”

This study found that St. John's wort treatment for two weeks induced finasteride metabolism and reduced its plasma exposure in healthy men.

research Age-related changes in endogenous glucocorticoids, gonadal steroids, endocannabinoids and their ratios in plasma and hair from the male C57BL/6 mice

11 citations , October 2020 in “General and comparative endocrinology”

This study found that age-related fluctuations in hormones and endocannabinoids in male C57BL/6 mice showed specific patterns, with peak values observed around 2.7 to 3.4 months, with these patterns seen in both plasma and hair but with different magnitudes.

research Rethinking Oral Minoxidil: Distinguishing the Hair-Growth Window from the Cardiovascular Threshold

March 2026 in “Journal of the American Academy of Dermatology”

Lower doses of oral minoxidil can promote hair growth without major heart risks.

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community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

75 upvotes 4 months ago

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

community Dut, 0.5mg once a day and never stop

441 upvotes 5 months ago

The conversation discusses the use of dutasteride (0.5 mg daily) for hair loss, with additional treatments like minoxidil, derma rolling, and nizoral shampoo. The user reports positive progress over two years with no significant side effects, emphasizing the importance of consistency and patience.

community Why do people on this sub die on the hill that fin/dut doesn't give regrowth in most cases?

in Research/Science 121 upvotes 1 year ago

Finasteride and dutasteride mainly stop hair loss, with little regrowth. Minoxidil is better for regrowth, but results differ per person.

community How Splitting Oral Minoxidil CHANGED Everything — After 2 Years of Topical Failure

in Minoxidil 32 upvotes 8 months ago

Switching from topical to oral minoxidil, specifically using split dosing, led to significant hair regrowth and reduced side effects for the user. The combination of oral minoxidil and finasteride proved more effective than previous topical treatments.

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learn Dutasteride

Heavy duty finasteride that comes with higher risks

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