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research Anti-PDGF Receptor β Antibody-Conjugated Squarticles Loaded with Minoxidil for Alopecia Treatment by Targeting Hair Follicles and Dermal Papilla Cells
Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
research Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B
The study found that insulin-like growth factor-I (IGF-I) promoted hair growth by extending the anagen phase and increasing hair growth rate in an organ culture model of 140 hair follicles from 3 individuals. IGF-I enhanced hair growth to 0.10 mm/day compared to 0.08 mm/day in the control group and maintained 70.8% of hair follicles in the anagen phase by day 12, versus 45.8% in controls. This effect was linked to IGF-I's anti-apoptotic properties and the upregulation of platelet-derived growth factors PDGF-A and PDGF-B, preventing hair follicles from entering the catagen phase.
research Faculty Opinions recommendation of Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B.
The study by Ahn SY et al. demonstrated that insulin-like growth factor 1 (IGF-I) played a crucial role in maintaining the anagen phase of hair growth. The research highlighted that the effect of IGF-I on hair growth was associated with its anti-apoptotic properties and the up-regulation of platelet-derived growth factors PDGF-A and PDGF-B. This finding suggested that IGF-I contributed to hair follicle health by preventing cell death and promoting factors that support hair growth.
research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner
PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
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5 / 5 resultscommunity Comprehensive Microneedling Guide
Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.
community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )
The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.
community Seriously confused about minoxidil's method of action
The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.
community 2 years later I managed to gain some ground (Hyperresponder)
The user regained most of their hair using Minoxidil, Finasteride, and Dermarolling. They found Dermarolling particularly effective, as it promotes growth factors and improves hair thickness.
community Surprisingly thorough study on He-Shou-Wu/Fo Ti
He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.