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Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride

research Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride

6 citations , July 2007 in “Organic Process Research & Development”

Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.

research Regeneration of Pd/C Finasteride Synthesis Catalyst by Extraction-Oxidation

January 2005 in “Industrial Catalysis”

The process effectively regenerates the Pd/C catalyst for finasteride synthesis.

research PD-1+ CXCR5− CD4+ T Cells Are Correlated with the Severity of Systemic Lupus Erythematosus

71 citations , May 2019 in “Rheumatology”

Tph cells are linked to the severity of systemic lupus erythematosus.

research Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege

53 citations , September 2013 in “Journal of Investigative Dermatology”

Hair follicle cells help protect against immune attacks by regulating T-cell activity.

Risk of Merkel Cell Carcinoma Progression After Treatment Discontinuation in Patients With an Objective Response to Anti-PD-(L)1 Immunotherapy

research Risk of Merkel Cell Carcinoma Progression After Treatment Discontinuation in Patients With an Objective Response to Anti-PD-(L)1 Immunotherapy

August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Longer immunotherapy treatment may improve outcomes for Merkel cell carcinoma patients.

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community Seriously confused about minoxidil's method of action

in Minoxidil 7 upvotes 3 years ago

The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.

community Currently crushing 3 (5mg) tablets of fin into my topical min. Anyone do the same? If so how much do you add.

in Treatment 186 upvotes 1 year ago

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

community How is there still no consensus on Topical Dutasteride in 2024?

in Finasteride/Dutasteride 147 upvotes 1 year ago

The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

community Dermastamp only with carrier/essential oil blend

in Microneedling 16 upvotes 2 years ago

A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.

community If minoxidil helped you with thinning temples or just in general please comment or upvote this!

in Research/Science 203 upvotes 2 years ago

Minoxidil, often combined with microneedling, has helped some users improve hair growth at the temples and hairline. Finasteride is also mentioned as a treatment, with mixed results on its effectiveness.

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