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GlossaryLead (Pb)

heavy metal toxic to humans, affecting hair growth

Lead, also known by its chemical symbol Pb (from the Latin "plumbum"), is a heavy metal that is toxic to humans and animals. It can accumulate in the body over time, leading to serious health issues such as neurological damage, especially in children. In the context of hair and alopecia, lead exposure can disrupt normal hair growth and contribute to hair loss by interfering with cellular processes and damaging hair follicles.

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PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

research PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis

26 citations, August 2019 in “Stem Cell Research & Therapy”

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis

12 citations, August 2022 in “Stem cell reviews and reports”

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair

research PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair

9 citations, November 2021 in “Frontiers in Cell and Developmental Biology”

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Light Emitting Diodes Technology-Based Photobiomodulation Therapy for Dermatology and Aesthetics: Recent Applications, Challenges, and Perspectives

research Light Emitting Diodes Technology-Based Photobiomodulation Therapy for Dermatology and Aesthetics: Recent Applications, Challenges, and Perspectives

8 citations, November 2020 in “Optics and Laser Technology”

LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.

research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis

3 citations, April 2022 in “Research Square (Research Square)”

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

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community Verteporfin mixing solute for transplants

in Treatment 12 upvotes 11 months ago

Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.

community Just sharing my holy grails. I have SO many baby hairs. I suffered with telogen effluvium and personally adding in a protein shake a day helped tremendously, I didn’t realize how packed full of vitamins they were. I used TOPICAL minox and had an elevated heart rate

in Treatment 6 upvotes 11 months ago

The user experienced an elevated heart rate from using topical Minoxidil and discontinued its use. They found that adding a daily protein shake helped with telogen effluvium.

community My 6 month hair transformation 🙂

in Progress Pictures 12 upvotes 1 month ago

Using RU58841 twice daily for 6 months led to noticeable hair improvement. Consistency and finding a quality source are key.

community Procyanidin B2 Topical Serum - The Cheap, Complete(ish) DIY Formula

in Research/Science 7 upvotes 1 year ago

The conversation is about a homemade hair loss treatment serum containing Procyanidin B2, Aloe Vera Gel, Coconut Oil, Castor Oil, and Rosemary Essential Oil. The main concern is finding an affordable source of Procyanidin B2 and ensuring its stability in the serum at room temperature.

community Post Low-Level Laser Light Therapy Syndrome (PLLLTS )

in Satire 6 upvotes 1 year ago

Hair loss discussion includes LLLT treatments and a satirical condition called PLLLTS, causing patients to resemble lighthouses and attract moths. Some users express concern about others taking the satire seriously.

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