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Glossary Patterned Scalp Underdevelopment

congenital condition causing irregular scalp development and hair growth

Patterned Scalp Underdevelopment (PSU) refers to a congenital condition where certain areas of the scalp do not develop properly, leading to irregular hair growth patterns or bald patches. This condition can be caused by genetic factors or developmental issues during fetal growth, and it may require medical evaluation to determine the best course of treatment or management.

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Research

5 / 1000+ results

research Androgenetic alopecia in men: the scale of the problem and prospects for treatment.

3 citations , January 1999 in “PubMed”

This review discusses the societal impact and treatment development for androgenetic alopecia, highlighting promising new drugs but reporting no new clinical results.

Self-Organizing Hair Peg-Like Structures From Dissociated Skin Progenitor Cells: New Insights for Human Hair Follicle Organoid Engineering and Turing Patterning in an Asymmetric Morphogenetic Field

research Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field

26 citations , January 2019 in “Experimental Dermatology”

This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.

research Alopecia.

22 citations , June 1980 in “International Journal of Dermatology”

The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.

research Male pattern baldness: current treatments, future prospects

40 citations , July 2008 in “Drug Discovery Today”

This review addresses the limited efficacy of current treatments for male pattern baldness and explains that emerging genetic insights could lead to more effective future therapies.

research New drugs under investigation for the treatment of alopecias

26 citations , January 2019 in “Expert Opinion on Investigational Drugs”

This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.

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Community Join

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community A Short Recap on PP405 and AAD 2026

in Update 5 months ago

PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Does everyone experiencing male pattern baldness have an oily scalp?

in Research/Science 18 upvotes 7 months ago

Male pattern baldness can occur with or without an oily scalp, but an oily scalp and seborrheic dermatitis can worsen the condition. Treatments like finasteride, minoxidil, and ketoconazole shampoo are used, and managing diet and scalp care can help control symptoms.

community Why does MPB only affect the scalp

in Research/Science 14 upvotes 1 year ago

Male pattern baldness (MPB) may be influenced by androgen receptors in scalp hair follicles and potentially poor blood flow. Transplanted hair is not immune to DHT, and factors like inflammation and scalp tension might also contribute to hair loss.

community Could male-pattern baldness have a secondary photobiological function? The Solar Window Hypothesis

11 upvotes 3 weeks ago

Male-pattern baldness might increase UVB exposure on the scalp, potentially affecting vitamin D and skeletal health. The hypothesis is debated, with some seeing it as a minor benefit in specific contexts.

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Learn

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learn Scalp Micropigmentation

What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.
Who is a good candidate for scalp micropigmentation? Good candidates for scalp micropigmentation include anyone experiencing hair loss or thinning.

learn Bimatoprost

What do the latest studies say about bimatoprost for scalp hair growth? Bimatoprost is approved only for eyelashes; a 30-person pilot found it beat a topical steroid on patches of alopecia areata, but the two registered Allergan trials in male pattern hair loss were never published and never taken further, so scalp use stays off-label and experimental.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

learn Fluocinolone

What type of hair loss is Fluocinolone recommended for, and how does it help inflamed scalps? Fluocinolone is a prescription topical corticosteroid used for inflammatory scalp conditions such as seborrheic dermatitis, scalp psoriasis and scarring alopecias. It calms inflammation rather than growing hair, it is not a treatment for pattern hair loss, and its labelling warns against prolonged use.

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Clinics

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Experts

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24
Trichologist
Kirsten J. Scalp
Greenville, SC, United States

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Kirsten J. Scalp