This review highlights Malassezia's dual role as both protective and pathogenic within the hair follicle ecosystem, noting its involvement in skin disorders and potential cancer progression, and calls for further studies to develop targeted treatments for related conditions.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study using a genetic mouse model found that S. aureus-driven dysbiosis sustains inflammatory skin side effects from EGFR inhibitors, suggesting prophylactic antibiotic treatment may reduce rash severity without fixing barrier defects.
5 citations
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June 2024 in “Cureus” This scoping review suggests there is a relationship between polycystic ovarian syndrome and vaginal microbiome dysbiosis, potentially linked to decreased Lactobacillus and increased pathogenic species.
3 citations
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June 2025 in “Biomedicines” This review discusses the potential link between gut microbiota alterations and the onset and progression of alopecia areata, identifying it as a possible pathogenetic factor and therapeutic target, but reports no new clinical results.
This study found that patients with androgenetic alopecia showed distinct scalp bacterial imbalances compared to healthy individuals, which were associated with unhealthy lifestyles. These microbial changes might contribute to follicular inflammation, potentially accelerating hair loss in these patients.