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DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

research DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

11 citations , March 2014 in “Journal of Investigative Dermatology”

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression

176 citations , February 2006 in “Cancer Research”

Patched1 helps prevent tumors by controlling cell growth.

research Epithelial-Mesenchymal Interactions Promote Hair Follicle Neogenesis and a New Stem Cell Niche in Adult Corneal Epithelium

August 2009 in “Mechanisms of Development”

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

research Sonic Hedgehog Signaling in the Regulation of Barrier Tissue Homeostasis and Inflammation

23 citations , October 2021 in “FEBS Journal”

Sonic Hedgehog helps keep skin and airway barriers healthy and reduces inflammation.

research A Slow-Cycling LGR5 Tumor Population Mediates Basal Cell Carcinoma Relapse After Therapy

105 citations , October 2018 in “Nature”

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

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community Progress pics Nov 23 to Nov 24

in Progress Pictures 11 upvotes 1 year ago

The user switched from finasteride and topical minoxidil to oral dutasteride and minoxidil, with plans to add RU58841, to improve hair growth and address a stubborn bald spot. Despite initial shedding, the user noticed thicker, darker hair and plans to continue the treatment or consider a hair transplant.

community Result - 5 months of topical minoxidil

in Progress Pictures 7486 upvotes 6 months ago

A 37-year-old man achieved significant hair regrowth in five months using topical minoxidil 5%, rosemary oil massages, and Nizoral 2% shampoo. His impressive results led to disbelief and admiration, with some attributing his success to being a "hyper responder."