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research 84 Partial restoration of scalp microbiota in alopecia areata with JAK inhibitors

November 2023 in “Journal of Investigative Dermatology”

In this study, patients with alopecia areata displayed altered scalp microbiota compared to healthy controls, and treatment with JAK kinase inhibitors largely restored these microbial changes, providing insights into the potential role of the skin microbiome in alopecia areata.

research Partial Response of Severe Alopecia areata to Cyclosporine A

30 citations , January 1999 in “Dermatology”

This study found that cyclosporine A may lead to partial hair regrowth in 50% of patients with severe alopecia areata who do not respond to standard treatments.

research Possible involvement of partial biotinidase deficiency in alopecia areata

6 citations , September 1996 in “Journal of the European Academy of Dermatology and Venereology”

This study found that biotin supplementation improved biotinidase activity and led to clinical remission in some patients with alopecia areata.

research Possible involvement of partial biotinidase deficiency in alopecia areata

1 citations , September 1996 in “Journal of the European Academy of Dermatology and Venereology”

In this study, biotin supplementation improved biotinidase activity and led to clinical remission in some patients with alopecia areata.

research Adjunctive Dupilumab Therapy in a Partial Responder to Baricitinib for Alopecia Areata

July 2025 in “SKIN The Journal of Cutaneous Medicine”

In this study, a patient with severe alopecia areata showed significant hair regrowth after 15 months of partial response to baricitinib and oral minoxidil, following the addition of dupilumab to their treatment regimen.

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and there is no evidence that salicylic acid helps hair regrow in it.

learn GHK-Cu

Do alopecia areata patches scar? And is there evidence for peptides? Alopecia areata patches usually still have living follicles and often regrow. One small trial of a cosmetic peptide lotion reported improvement, but no peptide is an approved treatment; see a dermatologist.

learn Centella

Sudden round bald patches: can centella cream help? There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn Vitamin D

Are topical Vitamin D treatments useful for alopecia? Small, short trials suggest topical vitamin D analogues such as calcipotriol may help some people with mild patchy alopecia areata. There is no trial evidence that they help pattern hair loss.

learn Baricitinib

JAK inhibitor pill used for severe alopecia areata

learn Bimatoprost

Is bimatoprost effective for people with alopecia areata? Bimatoprost is approved only for eyelashes; for alopecia areata the evidence is a few small studies with mixed results. Near the eyes it can darken the iris, a change its label says is likely to be permanent.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community A man in his 80s with full head of hair.

473 upvotes 5 months ago

Genetics play a major role in hair loss, with some people keeping a full head of hair into old age without using treatments like minoxidil or finasteride. Many express frustration over their own hair loss and the perceived unfairness of genetic differences.

community M25: Getting way too many DMs, so let’s do this here! AMA about Male Pattern Baldness, Hair Loss, and Products (100% Science-Backed )

1951 upvotes 5 months ago

Finasteride, dutasteride, and minoxidil are discussed as treatments for male pattern baldness. Finasteride and dutasteride are effective DHT blockers, while minoxidil is necessary for regrowth but must be used consistently.

community 21M Started young, treated early, but non-responder to dht blockers

56 upvotes 1 year ago

A 21-year-old male uses minoxidil, finasteride, and dutasteride for hair loss but still experiences progression with high DHT levels. Suggestions include increasing dosages, checking for deficiencies, considering a hair system, or consulting a specialist.

community Finasteride success for androgenic alopecia by a 27M physician (NO PICTURES)

4 upvotes 10 years ago

A 27-year-old male physician improved hair density using minoxidil 5% foam and finasteride 1mg every other day, with initial sexual side effects that subsided. He recommends trying finasteride for a year but warns against dutasteride due to potential liver effects.

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