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Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.

Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.