4 citations
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June 2017 in “Endocrine Reviews” Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
18 citations
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January 2019 in “European journal of histochemistry” This study found that in bovine skin, leptin and its receptor are expressed in the epidermis and hair follicles, suggesting a role in epidermis growth and hair follicle cycling through paracrine and autocrine mechanisms.
79 citations
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December 1990 in “Clinical endocrinology” This review explores the mechanisms of intratesticular control of steroidogenesis and indicates the need for further controlled studies; it presents no new experimental findings.
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
55 citations
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” This article discusses the interactions between keratinocytes and melanocytes in maintaining epidermal and hair follicle homeostasis, without reporting new experimental results.