Search

for
Search:

Research

5 / 1000+ results

research 3D Printing of Skin Equivalents with Hair Follicle Structures and Epidermal‐Papillary‐Dermal Layers Using Gelatin/Hyaluronic Acid Hydrogels

18 citations , July 2022 in “Chemistry - an Asian journal”

This study found that GelMA/HAMA bioink shows promise for 3D printing skin equivalents, as it effectively mimics the native skin's properties and supports hair follicle structure development.

research Cytokine loaded layer-by-layer ultrathin matrices to deliver single dermal papilla cells for spot-by-spot hair follicle regeneration

19 citations , December 2015 in “Journal of Materials Chemistry B”

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.

research Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system

23 citations , June 2015 in “Journal of Tissue Engineering and Regenerative Medicine”

This study demonstrated that a 3D air–liquid culture system using Wnt-CM-treated cells can induce hair regeneration in nude mice and may facilitate large-scale preparation for hair loss treatment.

research Generating LacZ-reporter transgenic mice to identify α1 (XIX) Collagen (Col19a1) expression in Dermal Papilla Cells

March 2016 in “Benha Veterinary Medical Journal”

This study investigated the gene Col19a1, finding its expression is specific to certain cells during hair follicle development in mice, suggesting its potential role in hair follicle morphogenesis.

research 918 Tissue engineered human hair follicles from genetically, environmentally and extrinsically reprogrammed dermal papilla cells

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study reports that incorporating Lef-1 transfected dermal papilla cells into human skin equivalents significantly promoted hair follicle differentiation and hair fiber growth, offering a potential advancement for managing skin loss.

View more "papillary dermal layer" in research →

Community Join

5 / 157 results

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

7 upvotes 5 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

community Scalp Massages in addition to Fin/Min and Microneedling

in Chat 8 upvotes 1 month ago

Scalp massages are considered a low-risk addition to hair loss treatments like finasteride, minoxidil, and microneedling, potentially offering minor benefits. Most users agree that while massages may improve blood circulation, significant results primarily come from the main treatments.

community Surprisingly thorough study on He-Shou-Wu/Fo Ti

13 upvotes 3 years ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

View more "papillary dermal layer" in community →

Learn

5 / 800 results

learn sh-Polypeptide-7

learn Epidermal Growth Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

How does SCUBE3 work on hair follicles compared to treatments like minoxidil or finasteride? Laboratory research in mice reports that SCUBE3, a protein released by dermal papilla cells, signals dormant follicles to grow through the TGF-β pathway downstream of Hedgehog; minoxidil and finasteride instead work on blood flow to the follicle and on DHT, and unlike SCUBE3 they have decades of human trial data behind them. SCUBE3 has not been tested in human clinical trials and is not available as a medicine.

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

View more "papillary dermal layer" in learn →

Experts

1 / 6 results

Hair Transplant Surgeon
Layers
Incomplete name
Visakhapatnam, India

Clinics

— no results

Try a deeper search in clinics →