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This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.

This review explores the role of Panx3 in skeletal formation and discusses its potential in developing new therapies for conditions like osteoarthritis, without presenting new clinical findings.

This study found that women with PCOS and female androgenetic alopecia had significantly higher serum pannexin-1 channel levels compared to those without PCOS, suggesting a potential role in hair loss etiology.

This study on feather pattern formation in chicken skin found that inhibiting gap junctional intercellular communication can lead to the emergence of new feather buds in specific spatial patterns, suggesting that GJIC may facilitate Turing-type periodic patterning by propagating inhibitory signals over long distances.

This study found that administering testosterone to pregnant rats altered connexin 26 and connexin 43 expression in the uterus, which could disrupt embryo implantation and cause early pregnancy loss.