19 citations
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September 2010 in “The American journal of pathology” This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.
October 2009 in “The American Journal of Gastroenterology” This case report suggests that isolated amylase deficiency can lead to failure to thrive in children, and pancreatic enzyme supplementation may improve associated symptoms.
1 citations
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June 2019 in “Current developments in nutrition” This case study reports that pancreatic enzyme replacement and fatty acid supplementation improved symptoms of fat malabsorption and essential fatty acid deficiency in a patient with EDS-4.
1 citations
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December 2013 in “Balkan Journal of Medical Genetics” This case study describes a 3.5-month-old girl with cystic fibrosis who experienced hair and skin depigmentation, which resolved after treatment with pancreatic enzymes and vitamins.
72 citations
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October 1992 in “Archives of Dermatology” This study describes five patients whose cystic fibrosis was initially indicated by a rash associated with protein-energy malnutrition, highlighting the importance of early symptom recognition for timely diagnosis and treatment.