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GlossaryPustulosis Palmoplantaris (Palmoplantar Psoriasis)

chronic skin condition causing pustules on palms and soles

Pustulosis Palmoplantaris (PPP) is a chronic skin condition characterized by the appearance of sterile pustules (blister-like sores filled with non-infectious pus) on the palms of the hands and the soles of the feet. It is often associated with psoriasis and can cause significant discomfort and pain, impacting daily activities.

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research Oral Treatment of Keratinizing Disorders of Skin and Mucous Membranes With Etretinate

31 citations , February 1982 in “Archives of dermatology”

Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.

research Challenging Regional Psoriasis and Ustekinumab Biotherapy: Impact of the Patterns of Disease

6 citations , January 2012 in “Journal of Biomedicine and Biotechnology”

Ustekinumab might work for severe psoriasis, but more research is needed to be sure.

research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions

January 2018 in “Springer eBooks”

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

research Appearance of Alopecia Areata During Treatment With Tildrakizumab for Severe Palmoplantar Psoriasis

1 citations , January 2026 in “Dermatology Reports”

Tildrakizumab may cause alopecia areata, but stopping it and using corticosteroids can regrow hair.

research Palmoplantar Psoriasis Complete Clearance Is Achieved Rapidly And Sustained With Ixekizumab Treatment In Adult And Pediatric Patients With Moderate-To-Severe Plaque Psoriasis

2 citations , September 2023 in “Journal of the American Academy of Dermatology”

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