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GlossaryPeptidyl Arginine Deiminase Type 2 (PADI2)

enzyme that converts arginine in proteins to citrulline

Peptidyl Arginine Deiminase Type 2 (PADI2) is an enzyme that converts arginine residues in proteins into citrulline, a process known as citrullination. This modification can affect protein function and is involved in various physiological processes, including the regulation of gene expression and the immune response. PADI2 has been implicated in conditions such as rheumatoid arthritis and certain types of alopecia, where abnormal citrullination may play a role in disease pathology.

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research Efficacy of Glucopyranosyldiacylglycerol from Padina Arborescens in Preventing Hair Loss

January 2020 in “생약학회지”

Padina arborescens and its component MOGG may help prevent hair loss through several actions, including blocking a hair loss-related enzyme.

research Co-Expression of PADI Isoforms During Progenitor Differentiation Enables Functional Diversity

2 citations , October 2023 in “Philosophical Transactions of the Royal Society B Biological Sciences”

Different PADI isoforms help cells develop diverse functions.

research Successful Immunosuppression in Childhood Alopecia Areata

3 citations , April 2011 in “Klinische Pädiatrie”

Immunosuppression therapy with methylprednisolone effectively treats childhood alopecia areata.

research A Brief Study on Alopecia Areata

April 2024 in “International Journal of Research Publication and Reviews”

Alopecia areata causes hair loss with varied treatment responses and frequent relapses.

research Diffuse Hair Loss And Clinical Endocrinology: New Insights

March 2013 in “Journal für Kardiologie (Krause & Pachernegg GmbH)”

Hormones significantly affect hair growth and loss, with potential for new treatments.

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