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This study found that systemic lupus erythematosus was diagnosed earlier in males than females, with a notable delay in diagnosis for females often due to confounding symptom overlaps with other conditions.

This study examined perceptions of stress as a cause of alopecia areata among individuals in a French online cohort, finding that over half of patients considered stress a contributing factor. Additionally, patients with less understanding of their condition experienced higher levels of perceived stigma.

This study found that mTOR gene expression was significantly increased and S6K1 activation was observed in skin samples from acne patients compared to healthy controls, suggesting mTORC1's involvement in acne pathogenesis.

This study observed high expression of mTOR pathway effectors in fibrous papules and TSC-associated angiofibromas, suggesting that topical rapamycin might be an effective treatment for fibrous papules.

This study found that topically applied melatonin exerts significant anti-aging effects on human scalp skin ex vivo, including increased SIRT1 expression and reduced mTORC1 pathway activity.