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research Effects of Transcutol P and Precirol ATO-5 on Percutaneous Absorption of Flutamide from Emulgels

June 2021 in “Pharmaceutical sciences”

This study found that flutamide emulgels with 1% Transcutol P enhanced percutaneous absorption through rat skin more effectively than other formulations tested.

research Abstract P5-09-21: Selective androgen receptor modulators (SARMs): Enobosarm as targeted therapy for the treatment of androgen receptor-positive breast cancer

2 citations , December 2013 in “Cancer research”

In this study, GTx-027, a selective androgen receptor modulator, significantly inhibited tumor growth in certain breast cancer models and showed good tolerance in a Phase II trial with postmenopausal women.

research P5 Assembly of hair keratins in thansfected cultured cells

April 1996 in “Journal of Dermatological Science”

Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride

research Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride

21 citations , January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology”

In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.

research Abstract P5-11-11: A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia (CIA)

February 2017 in “Cancer Research”

In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.

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Community Join

5 / 427 results

community Put P5P in my shampoo, reduced itch a lot!

4 upvotes 3 years ago

The user added P5P (vitamin B6) to their shampoo to reduce scalp itch, which improved significantly. They have been using finasteride for hair loss but are exploring additional treatments like topical antiandrogens and prolactin inhibitors.

community Still losing on fin 5x & dut 2x p/w (1.5 years in) - next steps advice

1 upvotes 1 year ago

The user has been using finasteride and minoxidil for 5 years with initial success but is now experiencing hair thinning despite increasing dutasteride usage. They are considering adjusting dutasteride frequency and possibly adding treatments like eucapil, minoxidil, and GHK-Cu peptides.

community Is anyone taking both boron and p5p to lower SHBG and Prolactin respectively? What are you experience on this?

5 upvotes 3 years ago

The user is applying topical finasteride with stemoxydine for hair loss and has noticed hair thickening but no regrowth after two months. They also report high SHBG and prolactin levels and a lack of morning erections, even on low doses of medication.

community If inhibiting DHT can cause Prolactin to increase then is the opposite also true?

4 upvotes 2 years ago

The conversation discusses using P5P (Vitamin B6) supplements to reduce elevated Prolactin levels and concerns about its potential effect on increasing DHT levels. The user is not currently using finasteride or any anti-androgens.

community M33. 5 month progress. FUE 3500 and Min+Fin.

in Transplants 60 upvotes 1 month ago

A user shared their 5-month progress after a hair transplant with 3500 FUE grafts, using Minoxidil and Finasteride. They used oral Minoxidil at 5mg.

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Learn

4 / 801 results

learn O-Cymen-5-Ol

learn Scalp Micropigmentation

Are there any side effects of scalp micropigmentation? Temporary redness, swelling, or itching may occur after scalp micropigmentation.

learn Overview

learn Vitamin B5

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