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Glossaryp53 Signaling Pathway (p53 Pathway)

regulates cell cycle and prevents cancer by responding to DNA damage

The p53 Signaling Pathway, also known as the TP53 Pathway, is a crucial cellular mechanism that helps regulate the cell cycle and prevent cancer. The p53 protein, often called the "guardian of the genome," activates in response to DNA damage or stress, leading to cell cycle arrest, DNA repair, or apoptosis (programmed cell death) to maintain genetic stability.

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research Priming Mobilization of Hair Follicle Stem Cells Triggers Permanent Loss of Regeneration After Alkylating Chemotherapy

32 citations , August 2019 in “Nature Communications”

Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.

research Cell Death in the Skin: Mechanisms and Implications

120 citations , February 2009 in “Apoptosis”

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

research Lentiviral Arrays for Live-Cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation

13 citations , June 2014 in “Molecular therapy”

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition

295 citations , September 2006 in “Cell Cycle”

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review

24 citations , January 2020 in “International Journal of Molecular Sciences”

Some plants with flavonoids may help treat hair loss and promote hair growth.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 10 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 2 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.