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GlossaryCYP17A1 (P450c17)

enzyme crucial for steroid hormone production

CYP17A1, also known as Cytochrome P450 17A1, is an enzyme that plays a crucial role in the production of steroid hormones. It is involved in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products, which are precursors for androgens and estrogens. This enzyme is essential for the synthesis of hormones that regulate various bodily functions, including metabolism, immune response, and sexual development.

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research A Review of Hyperandrogenism State in Polycystic Ovarian Syndrome

November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology”

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

research Detection of Urine Metabolites in Polycystic Ovary Syndrome by UPLC Triple-TOF-MS

23 citations, June 2015 in “Clinica Chimica Acta”

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

research Polycystic Ovarian Syndrome and Associated Hirsutism in Adolescents

7 citations, January 1992 in “Adolescent and pediatric gynecology”

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

research An Updated Overview of Polycystic Ovary Syndrome

1 citations, June 2019 in “Innovare journal of medical sciences”

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

research New Treatments of Hyperandrogenism and Hirsutism

9 citations, September 2000 in “Obstetrics and gynecology clinics of North America”

Hirsutism causes significant psychological distress in women.

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