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This study found that altered testosterone metabolism and changes in cytochrome P450 mono-oxygenase expression are significantly associated with cardiac hypertrophy in human hearts and spontaneously hypertensive rats.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.

This study found that in vitro treatments with 5alpha-reductase inhibitors and androgen receptor antagonists strongly stimulate VEGF expression in dermal papilla cells.

This review discusses the enzyme levels involved in dihydrotestosterone formation in androgenetic alopecia patients and reports no new results; the authors suggest these differences may lead to better treatments for men and women.