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Glossaryp38 MAPK pathway

regulates cellular responses to stress and inflammation

The p38 MAPK pathway, also known as the p38 mitogen-activated protein kinase pathway, is a signaling pathway in cells that responds to stress stimuli, such as inflammation and UV radiation. It plays a crucial role in regulating cellular processes like inflammation, cell growth, and apoptosis (programmed cell death). This pathway is significant in various diseases, including cancer and autoimmune disorders, and is a target for therapeutic interventions.

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research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo

6 citations, May 2022 in “Aging”

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

In Vitro Hair Growth-Promoting Effects of Araliadiol via the p38/PPAR-γ Signaling Pathway in Human Hair Follicle Stem Cells and Dermal Papilla Cells

research In Vitro Hair Growth-Promoting Effects of Araliadiol via the p38/PPAR-γ Signaling Pathway in Human Hair Follicle Stem Cells and Dermal Papilla Cells

December 2024 in “Frontiers in Pharmacology”

Araliadiol may promote hair growth like minoxidil without being toxic.

research Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK-ERK Signaling Pathway

45 citations, April 2013 in “Cell Transplantation”

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

research Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways

14 citations, September 2018 in “International Journal of Molecular Sciences”

Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.

research Regulation of Involucrin Gene Expression

138 citations, June 2004 in “Journal of Investigative Dermatology”

Involucrin gene expression is controlled by specific proteins and signaling pathways.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 735 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Aronia Chokeberry and Cyanidin 3-O-arabinoside for Hair Growth (AGA) Study

in Research/Science 14 upvotes 11 months ago

A natural compound called C3A from Aronia Chokeberry can help prevent hair loss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.