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GlossaryLPAR6 (P2Y5)

protein receptor involved in hair growth and maintenance

LPAR6, also known as Lysophosphatidic Acid Receptor 6, is a protein encoded by the LPAR6 gene. This receptor is involved in cell signaling and plays a crucial role in hair growth and maintenance. Mutations in the LPAR6 gene can lead to conditions like hypotrichosis, a form of hair loss characterized by sparse and fragile hair.

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research Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, P2Y5/LPA6

253 citations , April 2009 in “Journal of Biological Chemistry”

p2y5, now called LPA6, is a receptor important for human hair growth.

research LPA-Producing Enzyme PA-PLA1α Regulates Hair Follicle Development by Modulating EGFR Signaling

151 citations , August 2011 in “The EMBO Journal”

The enzyme PA-PLA1α is important for proper hair follicle development.

research Lysophospholipid Mediators in Health and Disease

49 citations , November 2021 in “Annual review of pathology”

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

research A Missense Mutation in the P2RY5 Gene Leading to Autosomal Recessive Woolly Hair in a Syrian Patient

13 citations , November 2009 in “Journal of Dermatological Science”

A gene mutation causes woolly hair in a Syrian patient.

research Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells

81 citations , December 2009 in “Journal of Dermatological Science”

Fat tissue stem cells may help increase hair growth.

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