This review discusses recent genome-wide association studies identifying novel candidate genes for various forms of alopecia, providing insights into their pathogenesis and molecular mechanisms, but reports no new clinical results.
210 citations
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February 2008 in “Nature genetics”
This study found mutations in the P2RY5gene that are linked to autosomal recessive woolly hair in Pakistani families, implicating it in hair texture determination.
1 citations
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February 2009 in “Journal of Investigative Dermatology”
This review discusses insights into the role of lipase H in controlling hair form and texture, emphasizing genetic mutations linked to autosomal recessive woolly hair/hypotrichosis, and reports no new experimental results.