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GlossaryLPAR6 (P2RY5)

protein receptor involved in hair growth and maintenance

LPAR6, also known as Lysophosphatidic Acid Receptor 6, is a protein encoded by the LPAR6 gene. This receptor is involved in cell signaling and plays a crucial role in hair growth and maintenance. Mutations in the LPAR6 gene can lead to conditions like hypotrichosis, a form of hair loss characterized by sparse and fragile hair.

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research Disruption of P2RY5, an Orphan G Protein–Coupled Receptor, Underlies Autosomal Recessive Woolly Hair

210 citations, February 2008 in “Nature genetics”

Mutations in the P2RY5 gene cause autosomal recessive woolly hair.

research A Missense Mutation in the P2RY5 Gene Leading to Autosomal Recessive Woolly Hair in a Syrian Patient

13 citations, November 2009 in “Journal of Dermatological Science”

A gene mutation causes woolly hair in a Syrian patient.

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