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Glossaryp27Kip1 (p27)

protein that inhibits cell cycle progression by regulating CDKs

p27Kip1, also known as p27 or CDKN1B, is a protein that helps regulate the cell cycle by inhibiting cyclin-dependent kinases (CDKs). This regulation is crucial for controlling cell growth and division, and disruptions in p27Kip1 function can lead to uncontrolled cell proliferation, which is a hallmark of cancer.

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research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer

18 citations, April 2011 in “International Journal of Molecular Medicine”

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

research HIF-2α/ARNT Complex Regulates Hair Development via Induction of p21 Waf1/Cip1 and p27 Kip1

4 citations, March 2014 in “The FASEB Journal”

The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.

research Coverage of Large Sacral Pressure Sores with the Gluteal Perforator Flap

September 2006 in “Plastic and Reconstructive Surgery”

The SGAP flap effectively treats large sacral pressure sores with good results and minimal complications.

research Recalcitrant Alopecia Areata Improved with Intralesional Polydeoxyribonucleotide Injection: Two Case Reports

January 2015 in “프로그램북(구 초록집)”

Two patients with stubborn hair loss grew hair after PDRN injections.

research Bone Morphogenetic Protein Signaling Regulates the Size of Hair Follicles and Modulates the Expression of Cell Cycle-Associated Genes

92 citations, November 2006 in “Proceedings of the National Academy of Sciences of the United States of America”

BMP signaling controls hair follicle size and cell growth by affecting cell cycle genes.

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