April 2023 in “Journal of Investigative Dermatology” This study presents a new long-term 3D skin model using cells from mature donor skin, showing significant features of skin aging, such as decreased cellular proliferation and hyaluronan content.
29 citations
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March 2014 in “PloS one” In this study, Astragaloside IV was found to inhibit apoptosis-related pathways in hair follicles of mice, suggesting it may serve as an alternative therapy for hair loss.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
December 2014 in “TDX (Tesis Doctorals en Xarxa)” This study suggests that while cellular senescence impairs epidermal stem cells in aging, it also serves an essential role during embryonic development, highlighting its dual functional nature.
42 citations
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.
