May 2020 in “Archives of Medical Science” This study reports that androgenetic alopecia patients exhibit reduced CK15 and tropoelastin expression and increased cellular senescence markers, indicating tissue damage in affected hair follicles and surrounding structures.
58 citations
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May 2004 in “British Journal of Dermatology” This study found that topical immunotherapy affects angiogenesis and immune cell ratios in the scalp, potentially offering insights into the mechanisms underlying alopecia areata.
1 citations
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October 2021 in “Clinical, Cosmetic and Investigational Dermatology” In this study on cultured human dermal papilla cells, researchers found that niacinamide may enhance hair growth by reducing oxidative stress-induced cell senescence and delaying catagen entry, suggesting potential applications against hair loss.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that apocynin restored COL17A1 expression in human keratinocytes and reduced UVB-induced cellular senescence, DNA damage, and cell cycle arrest.
19 citations
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June 2008 in “Journal of Investigative Dermatology” This study found that transgenic mice with expression of HPV16 E6/E7 oncogenes showed improved ear tissue regeneration, including hair follicles and cartilage, without tumor formation.