research Postzygotic Mutations in Beta-Actin Are Associated with Becker’s Nevus and Becker’s Nevus Syndrome
Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.
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5 / 1000+ resultsresearch Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
In this study, silencing P-cadherin in human scalp hair follicles reduced melanogenesis and associated protein expression, suggesting P-cadherin is crucial for normal hair pigmentation via GSK3β-mediated Wnt signaling.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
research Foxp3 Post-translational Modifications and Treg Suppressive Activity
This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.
research COVID-19 and endocrine and metabolic diseases. An updated statement from the European Society of Endocrinology
This review discusses the emerging "endocrine phenotype" of COVID-19, highlighting the implications for managing diabetes, obesity, vitamin D deficiency, and other endocrine conditions in affected patients.
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4 / 1000+ resultscommunity P-1075: a BETTER version of Minoxidil
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.
community Topical finasteride (P-3074) inhibits scalp DHT up to 70%
Topical finasteride (P-3074) can inhibit scalp DHT by up to 70%, with some users experiencing systemic absorption similar to oral use. Users discuss varying application frequencies and concentrations, with some noticing side effects when overused.
community How does Pedro P have a full head of hear. I'm losing mine and will be bald within 1 year. I'm not even 30yo.
Pedro Pascal's full head of hair is likely due to genetics, finasteride, and possibly hair transplants. Many actors use finasteride to maintain their hair.
community Still losing on fin 5x & dut 2x p/w (1.5 years in) - next steps advice
The user has been using finasteride and minoxidil for 5 years with initial success but is now experiencing hair thinning despite increasing dutasteride usage. They are considering adjusting dutasteride frequency and possibly adding treatments like eucapil, minoxidil, and GHK-Cu peptides.
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