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Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

44 citations , May 2012 in “Endocrinology”

High levels of androgens during early development may cause PCOS-like symptoms.

research Development of Polycystic Ovary Syndrome: Involvement of Genetic and Environmental Factors

232 citations , December 2005 in “Andrology”

PCOS is caused by both genetics and environmental factors like diet and obesity.

research Androgen Action in the Ovary

62 citations , August 2018 in “Frontiers in Endocrinology”

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

research Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update

258 citations , July 2016 in “Reproductive Biology and Endocrinology”

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

research Genetic Defects of Female Sexual Differentiation

November 2016 in “Elsevier eBooks”

Genetic mutations can affect female sexual development, requiring personalized medical care.

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community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 2 months ago

Genetic differences in hair follicles affect hair loss patterns. Treatments discussed include finasteride, dutasteride, minoxidil, and RU58841.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

in Female 55 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community 24 y/o woman diagnosed with AGA today. Scared and confused.

8 upvotes 9 years ago

A 24-year-old woman being diagnosed with androgenic alopecia (AGA) who is scared and confused about her hair loss, and the treatment options of Minoxidil, finasteride, RU58841, spironolactone, and possibly a biopsy.

community IVF process on Finasteride and effects of stopping finasteride.

in Finasteride/Dutasteride 136 upvotes 4 days ago

Concerns about finasteride affecting sperm quality and embryo abnormalities during IVF. The user plans to stop finasteride for 6 months and use minoxidil, microneedling, a red light cap, and saw palmetto shampoo to manage hair loss.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

in Transgender 2257 upvotes 5 months ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

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