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research Identification of functional circRNAs regulating ovarian follicle development in goats

8 citations , September 2024 in “BMC Genomics”

In this study, researchers found that the novel gene circCFAP20DC enhances the proliferation of goat follicular granulosa cells by activating the RB pathway, facilitating their progression from the G1 to S phase during follicular development.

research Key Aspects Of The Development Of The Menstrual And Ovarian Cycle In Adolescent Girls

December 2022 in “Journal of Pharmaceutical Negative Results”

This article discusses the factors contributing to menstrual-ovarian cycle disorders among adolescent girls in Bukhara and emphasizes the need for early preventive measures to enhance reproductive health.

research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

44 citations , May 2012 in “Endocrinology”

This review discusses the etiology of polycystic ovary syndrome, emphasizing the role of genetic and environmental factors, and reports no new experimental findings.

research CASE OF EARLY PUBERTAL DEVELOPMENT IN A 3-YEAR-OLD GIRL: CONSIDERING RARE PERIPHERAL CAUSES

April 2025 in “International Journal For Multidisciplinary Research”

This case report details the investigation and management of a 3-year-old girl with precocious pseudopuberty due to a Sertoli-Leydig cell tumor, highlighting the importance of early recognition and accurate diagnosis for effective treatment and prognosis.

research Androgen synthesis, metabolism and action in the developing ovarian follicle

December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)”

In this study, using a 3D culture model, researchers observed that developmental stage and androgen levels influenced murine follicle growth, which may inform treatment for women with low ovarian reserve but cautions against excessive androgen exposure.

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community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.

15 upvotes 8 years ago

Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.

community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 1 year ago

Genetic differences in hair follicles affect hair loss patterns. Treatments discussed include finasteride, dutasteride, minoxidil, and RU58841.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

55 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community IVF process on Finasteride and effects of stopping finasteride.

138 upvotes 9 months ago

Concerns about finasteride affecting sperm quality and embryo abnormalities during IVF. The user plans to stop finasteride for 6 months and use minoxidil, microneedling, a red light cap, and saw palmetto shampoo to manage hair loss.

community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

2264 upvotes 1 year ago

A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

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