August 2013 in “Fertility and Sterility” This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.
7 citations
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September 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that the ovarian stromal area to total ovarian area ratio alone is not a strong predictor of biochemical hyperandrogenism in Thai women with PCOS, but combining it with clinical hyperandrogenism improves prediction.
49 citations
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November 2019 in “Egyptian Journal of Medical Human Genetics” This review discusses the role of CYP gene polymorphisms in exacerbating hyperandrogenism in women with PCOS and reports no clinical results; further validation of this hypothesis is needed.
November 2022 in “Journal of the Endocrine Society” This case report describes a rare instance of virilizing androgen production due to an ovarian serous cystadenoma in a 59-year-old woman, with testosterone levels normalizing after its removal.
77 citations
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October 1986 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that nafarelin treatment significantly reduced androgen levels and improved hirsutism symptoms in women, suggesting it may be useful for managing this condition.
