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GlossaryOsteoarthritis

chronic joint condition causing cartilage breakdown and pain

Osteoarthritis (OA), also known as Degenerative Joint Disease, is a chronic condition characterized by the breakdown of cartilage in the joints, leading to pain, stiffness, and reduced mobility. It commonly affects weight-bearing joints such as the knees, hips, and spine, and is often associated with aging, repetitive stress, or joint injury.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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research Inhibition of a Signaling Modality Within the Gp130 Receptor Enhances Tissue Regeneration and Mitigates Osteoarthritis

1 citations, March 2023 in “Science Translational Medicine”

Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.

research Cell and Cell-Free Therapies in Osteoarthritis

10 citations, November 2021 in “Biomedicines”

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.

research Anti-Aging Potential of Platelet Rich Plasma: Evidence from Osteoarthritis and Applications in Senescence and Inflammaging

1 citations, August 2023 in “Bioengineering”

PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.

research Prospective Observational Study of a Non-Arthroscopic Autologous Cartilage Micrografting Technology for Knee Osteoarthritis

November 2023 in “Bioengineering”

AMT® is effective and safe for early-stage knee osteoarthritis.

research Resolution of Elevated Alkaline Phosphatase After Joint Replacement in Severe Osteoarthritis

October 2023 in “Journal of the Endocrine Society”

Joint replacement surgery normalized high alkaline phosphatase levels in a patient with severe osteoarthritis.

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community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 52 upvotes 6 months ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community How uninformed the general public is about hair loss

in Chat 317 upvotes 1 year ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.