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Glossary Oral Supplements

products taken by mouth to supplement diet with nutrients

Oral supplements, also known as oral dietary supplements, are products taken by mouth that contain vitamins, minerals, herbs, amino acids, or other substances intended to supplement the diet. They are often used to address nutritional deficiencies, support overall health, or target specific health concerns, such as hair growth or immune function.

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Research

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research Clinical Efficacy of Topical or Oral Soy Supplementation in Dermatology: A Systematic Review

2 citations , June 2023 in “Journal of clinical medicine”

This review found that both oral and topical soy-based products showed positive effects on various skin-related outcomes, including aging signs and skin barrier function, but topical applications were more likely to improve skin barrier status compared to oral supplementation.

research Oral Supplementation of Nicotinamide Mononucleotide (NMN) Improves Hair Quality and Subjective Perception of Hair Appearance in Middle-Aged Women

September 2025 in “Cosmetics”

In this study, oral supplementation with NMN for 12 weeks in middle-aged Japanese women significantly increased hair growth density and diameter and improved subjective assessments of hair texture and quality of life, with no significant changes in hair hormone concentrations observed.

Oral Supplementation with L-Cystine, Serenoa Repens, Cucurbita Pepo, and Pygeum Africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, Placebo-Controlled, Randomized Clinical Study

research Oral Supplementation with l-Cystine, Serenoa repens, Cucurbita pepo, and Pygeum africanum in Chronic Telogen Effluvium and Androgenetic Alopecia: A Double-Blind, Placebo-Controlled, Randomized Clinical Study

July 2024 in “Skin Appendage Disorders”

This study found that after 6 months of taking an oral supplement, patients with chronic telogen effluvium or androgenetic alopecia experienced a statistically significant increase in hair density and overall improved hair appearance compared to those taking a placebo, with the supplement being well tolerated.

research Efficacy of a new combination of a microemulsion and oral supplementation for androgenetic alopecia: an interventional multicentric study

January 2022 in “Italian journal of dermatology and venereology”

This study reported that a natural complex showed good efficacy in improving hair loss in both male and female androgenetic alopecia over six months.

research Oral supplementation in female telogen effluvium: a clinical and instrumental objective evidence of efficacy and tolerability of new oral cosmetic treatment

January 2023 in “Italian journal of dermatology and venereology”

This study found that a new oral supplement with sulfurated amino acids and trace elements effectively improved hair growth and reduced hair loss in women with telogen effluvium and mild to moderate androgenetic alopecia.

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Community Join

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community Oral Supplementation of Nicotinamide Mononucleotide (NMN) Improves Hair Quality and Subjective Perception of Hair Appearance in Middle-Aged Women

2 upvotes 11 months ago

Oral supplementation of Nicotinamide Mononucleotide (NMN) improves hair quality and appearance in middle-aged women. However, it may reduce total hair density, possibly due to seasonal shedding.

community NMN supplementation experiences?

2 upvotes 8 months ago

The conversation discusses experiences with NMN supplementation for hair growth, with some users reporting increased hair growth activity and others seeing no significant changes. OP has been using dutasteride and oral minoxidil, and recently added NMN, noticing increased shedding, which they hope indicates new hair growth.

community Under-eye wrinkle appeared after 4 weeks of oral minoxidil use, along with significant dark circles and under-eye puffiness.

38 upvotes 3 years ago

The user's experience with oral minoxidil, which resulted in under-eye wrinkles; other users sharing their experiences and advice regarding hair loss treatments such as topical minoxidil, finasteride, RU58841, and collagen supplementation.

community Copper Literally Saved My Life (and My Baldness)

31 upvotes 1 year ago

Oral copper supplementation significantly improved hair regrowth for someone who experienced severe hair loss after stopping minoxidil, suggesting copper deficiency might hinder minoxidil's effectiveness. The user now only takes copper and occasionally uses microneedling, recommending others to try copper if minoxidil alone isn't effective.

community Topical Dutasteride and creatine

3 upvotes 8 months ago

The conversation discusses using topical dutasteride as an alternative to oral finasteride to prevent hair shedding caused by creatine supplementation. Users share experiences with finasteride, dutasteride, and creatine, noting potential side effects and effectiveness concerns with topical treatments.

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Learn

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learn zinc PCA

Should zinc be taken orally or applied topically for better results in hair growth? Oral zinc supplementation is generally more effective for promoting hair growth than topical application.

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

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