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research Combination treatment of extensive and recalcitrant alopecia areata with oral and topical steroids with topical minoxidil: An open-label study of efficacy and safety in pediatric patients

January 2016 in “Indian Journal of Paediatric Dermatology”

This study found that a combination treatment using oral and topical steroids with topical minoxidil was well-tolerated in children with severe recalcitrant alopecia areata, showing good responses except in alopecia universalis cases.

research Comparison of autologous platelet concentrates and topical steroids on oral lichen planus: a systematic review and meta-analysis

1 citations , June 2024 in “BMC Oral Health”

In this study, autologous platelet concentrates and topical steroids similarly reduced lesion size, Thongprasom scale, and pain in oral lichen planus patients, suggesting autologous platelet concentrates as a potential alternative treatment.

research Comparative efficacy and safety of systemic steroids, oral JAK inhibitors and Contact Immunotherapy in the Treatment of severe alopecia areata: a systematic review and network meta-analysis

3 citations , July 2024 in “Archives of Dermatological Research”

This study found that oral dexamethasone and DPCP were more effective for treating severe alopecia areata compared to oral ritlecitinib and baricitinib, but oral ritlecitinib had better safety outcomes.

research Alteration of serum and tissue tumor necrosis factor alpha levels: A possible mechanism of action of oral pulse steroids in the treatment of alopecia areata

5 citations , October 2018 in “Journal of Cosmetic Dermatology”

This study found that oral pulse steroids significantly reduced serum and tissue levels of TNF-α in patients with alopecia areata, correlating with clinical improvement.

research A clinico-pathological study of Neogynon as a new oral contraceptive steroid.

2 citations , March 1976 in “PubMed”

In this study, Neogynon was found to be 100% effective as a contraceptive, with no observed failures in 3129 cycles among 184 women, while side effects included changes in endometrial patterns and some central nervous system effects.

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Community Join

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community Ru-58841 vs KX-826/pyrilutamide while on steroids

4 upvotes 1 year ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community Does going 2.5mg to 5mg oral minoxidil provokes another shed?

2 upvotes 2 months ago

The user has been using 1mg finasteride and started 2.5mg oral minoxidil for more hair regrowth, considering increasing to 5mg but is concerned about potential shedding. They also underwent mesotherapy but feel it may not be necessary, and are advised to use a steroid lotion for scalp redness.

community Second shed and more abnormalities

in Treatment 1 upvotes 2 years ago

The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.

community Running Gear- Preemptive Treatment

in Product 10 months ago

A 51-year-old on TRT plans to use steroids and is concerned about hair loss, considering topical treatments like Hair Rescue with RU58841 and finasteride, along with Nioxin shampoo. They are cautious about using oral DHT blockers due to potential interactions with steroids like Tren and Anavar.

community Comprehensive stack. Is it working?

in Is this regrowth? 9 upvotes 1 year ago

The user is using a comprehensive hair loss treatment including oral dutasteride, minoxidil (both oral and topical), topical finasteride, RU58841, ketoconazole shampoo, and a derma roller, while also using anabolic steroids. Opinions vary, with some users noting stability or slight improvement, while others suggest the treatment may not be effective due to anabolic use.

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Learn

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learn Prednisolone

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

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