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Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in Screening

research Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in the Screening

March 2013 in “Journal of pediatric nursing”

This case report presents a 14-year-old girl with type A insulin resistance, illustrating diagnostic processes to differentiate it from type 2 diabetes in the context of pediatric obesity and hyperglycemia.

research Hypoglycemic activity of extracts of Chamaecyparis obtusa var. formosana leaf in rats with hyperglycemia induced by high-fat diets and streptozotocin

10 citations , November 2019 in “Journal of Traditional and Complementary Medicine”

This study found that oral treatment with Chamaecyparis obtusa var. formosana leaf extracts improved glucose metabolism and reduced insulin resistance in hyperglycemic rats, suggesting potential as a diabetes health supplement.

research Post-Fundoplication Late Dumping Syndrome in an Adult Diagnosed by Provocative Modified Oral Glucose Tolerance Test

October 2018 in “The American Journal of Gastroenterology”

This case report highlights a rare instance of late dumping syndrome following fundoplication in an adult, diagnosed using an oral glucose tolerance test, illustrating its potential for reducing diagnostic delays.

research A Clinical Approach to Severe Insulin Resistance

32 citations , January 2007 in “KARGER eBooks”

This review discusses severe insulin resistance syndromes, highlighting their diagnostic challenges, potential novel therapies like leptin replacement, and suggests metformin and lifestyle changes in its absence; no new clinical results are reported.

research A modified laparoscopic sleeve gastrectomy for the treatment of diabetes mellitus type 2 and metabolic syndrome in obesity

13 citations , March 2012 in “The American Journal of Surgery”

This study found that modified laparoscopic sleeve gastrectomy in patients with type 2 diabetes and obesity reduced ghrelin levels, improved glycemic and insulin levels, and resulted in significant weight loss.

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community Is this Better Than Topical Minoxidil? Topical Diazoxide

6 upvotes 1 year ago

Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

55 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Oral minoxidil users, for your interest

61 upvotes 1 day ago

Taking oral minoxidil in the morning may lead to better hair growth results compared to taking it at night. Some users combine it with finasteride and topical treatments, and there are discussions about splitting doses or adjusting timing to maximize benefits.

community Oral Minoxidil Shed Persisting for Almost a year

4 upvotes 1 day ago

The user has been experiencing persistent hair shedding for almost a year after starting oral minoxidil 2.5 mg, despite being on oral finasteride 1 mg for over a year. They report major thinning, especially at the hairline, and are seeking advice on similar experiences.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

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