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Glossary Oral Hairy Leukoplakia

white, hairy patches on the tongue caused by Epstein-Barr virus

Oral Hairy Leukoplakia (OHL) is a condition characterized by white, hairy-looking patches on the sides of the tongue. It is caused by the Epstein-Barr virus (EBV) and is often seen in individuals with weakened immune systems, such as those with HIV/AIDS. The condition is generally benign but can be an indicator of underlying immunosuppression.

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Research

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research The development of oral hairy leukoplakia during JAK inhibitor baricitinib therapy

September 2023 in “JAAD case reports”

In this review, the authors noted that while baricitinib, a treatment for refractory rheumatoid arthritis and severe alopecia areata, shows promising efficacy, it may pose risks of serious infections and malignancy due to immune downregulation.

research Oral Treatment of Keratinizing Disorders of Skin and Mucous Membranes With Etretinate

31 citations , February 1982 in “Archives of dermatology”

This study found that oral etretinate improved skin conditions like erythrodermic and pustular psoriasis, although less so for psoriasis vulgaris and lichen planus, with notable side effects including cheilitis and mucous membrane dryness.

research Cutaneous Manifestations of the Acquired Immunodeficiency Syndrome Update 1987

76 citations , December 1987 in “International Journal of Dermatology”

This article reviews the various skin manifestations associated with AIDS and does not report new clinical findings; the authors highlight the diverse range of dermatologic conditions seen in affected individuals.

research Mucocutaneous manifestations in children with human immunodeficiency virus infection

16 citations , January 2010 in “Indian Journal of Dermatology, Venereology and Leprology”

This review discusses the role of skin manifestations as early markers and prognostic indicators of HIV infection in children but reports no new clinical results.

research Non‐infective mucocutaneous presentations of human immunodeficiency virus infection

8 citations , August 1997 in “Australasian Journal of Dermatology”

This review discusses the distinctive non-infective skin presentations of HIV infection from a dermatological perspective and reports no new clinical findings.

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Community Join

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community Hair became curly, dry, and lifeless after starting oral minoxidil – is this the “ugly phase” or permanent?

in Minoxidil 15 upvotes 6 months ago

Oral minoxidil caused changes in hair texture, making it curly, dry, and lifeless, raising concerns about whether this is a temporary phase or permanent. Users discussed potential side effects of oral minoxidil, including heart issues, and suggested consulting a dermatologist and monitoring health markers.

community How much excessive body hair with oral min?

in Minoxidil 12 upvotes 11 months ago

Oral minoxidil can lead to increased body hair growth, especially in areas where hair already exists, but results vary by individual. Some users report noticeable changes within a few months, while others see minimal impact; concerns about excessive hair growth are common, but many prioritize hairline improvement over body hair concerns.

community Oral minoxidil in EU (hair is law)

in Minoxidil 6 upvotes 5 months ago

The conversation is about finding a reliable source for oral minoxidil in the EU, as the original supplier is out of stock. The user is currently using finasteride and oral minoxidil for hair loss treatment.

community Oral minoxidil gives hair everywhere except scalp,plss help

in Minoxidil 41 upvotes 1 year ago

Oral minoxidil is causing body hair growth but not improving scalp hair, despite using dutasteride and finasteride. Users suggest waiting longer for results, checking vitamin levels, and considering additional treatments like topical minoxidil, dermarolling, and supplements.

community Oral Minoxidil worse hair after 1 year

in Progress Pictures 41 upvotes 2 years ago

The user switched from topical to oral Minoxidil and Finasteride but saw no improvement after a year, with hair appearing thinner. They recently switched to Dutasteride, hoping for better results.

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Learn

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learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

How does spironolactone help reduce hair loss when used in topical or oral treatments? Studies report that spironolactone slows androgen-driven follicle miniaturisation by blocking androgen receptors, with most evidence in women and mostly alongside minoxidil; it is a prescription drug and its use for hair loss is off-label.

learn Vitamin B5

Is Vitamin B5 more effective as an oral supplement or in topical hair care products? Vitamin B5 is not proven to be significantly effective for hair loss in either form.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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