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Research

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research 410 Oral dysbiosis in palmoplantar pustulosis patients with arthro-osteosis

April 2018 in “Journal of Investigative Dermatology”

This study found that palmoplantar pustulosis patients exhibited oral dysbiosis, particularly among those with pustulotic arthro-osteosis, as compared to healthy controls.

research Clinical Translation of Microbiome Research in Alopecia Areata: A New Perspective?

2 citations , May 2022 in “Cosmetics”

This review explores the potential roles of the gut and skin microbiome in alopecia areata, suggesting topical and systemic strategies for managing the condition, but it reports no new clinical results.

research Rare and Underappreciated Causes of Polycystic Ovarian Syndrome

January 2022 in “IntechOpen eBooks”

This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.

research Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues

2 citations , November 2022 in “Bioscience Reports”

This review explores the similarities between polycystic ovary syndrome and hemochromatosis in terms of iron overload and suggests that addressing gut dysbiosis might help manage iron levels in these conditions.

research Polycystic Ovarian Disease: Current Insights and therapeutic Strategies

December 2024 in “African Journal of Biomedical Research”

This review discusses various risk factors and potential therapeutic interventions for PCOS but reports no new clinical results.

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Community Join

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community Microneedling Isn’t Snake Oil — It’s Evidence-Based. Let’s Talk Studies, Not Fear.

41 upvotes 1 year ago

Microneedling is supported by research as an effective adjuvant treatment for hair loss, especially when combined with Minoxidil or Finasteride, with minimal side effects if done properly. Concerns about long-term safety and potential risks like infection or fibrosis remain, but many users report positive results.

community Scalp Microbiomes and AGA. The good, the bad and suggested treatments: Summation of studies

3 upvotes 3 years ago

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community five yeras journey fighting hairloss

157 upvotes 1 month ago

The user has been battling hair loss for five years using Minoxidil, Finasteride, and Dutasteride. Despite some improvements, hair loss persists, and they are considering dietary changes and other treatments for seborrheic dermatitis and hyperhidrosis.

community Inflammation's surprising role in shrinking hair follicles and AGA

in Technology 66 upvotes 4 months ago

Inflammation plays a significant role in hair follicle miniaturization and androgenetic alopecia, with treatments like ketoconazole shampoo, minoxidil, and finasteride being used to address it. Users discuss the benefits of anti-inflammatory treatments and peptides like KPV, alongside traditional hair loss treatments, to improve scalp health and hair quality.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

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Clinics

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